Nope, that doesn't apply with DSMlink. You can advance timing as much or as little as you want, independent of injector size.
Leon, larger injectors will PROBABLY make it very difficult for you to pass aircare. I needed Fraser's 450s before I could pass, and I'm only running 550s. Really though, it's a pretty small job changing the injectors, so go big, (I've heard FIC 950s work VERY well), and just keep your stockers to swap back on every two years, no biggy.
I'm on 550s, and seeing 93+% duty cycle. I probably COULD have gone bigger. On the other hand, you really don't have to go overboard...if you don't plan on running 11s, then I doubt if you'll need larger than 720cc injectors. Or you could be Fraser and run
almost 11s on 510s.